Gamma-aminobutyric acid, also known as GABA, is a neurotransmitter that helps send messages between the brain and the nervous system.

It is produced in the brain from glutamate. This process is catalyzed by the active form of vitamin B6 and the enzyme glutamate decarboxylase (GAD).

Its main function is to reduce the activity of nerve cells in the nervous system. A good amount of emerging research has found that it could play a role in many conditions, including depression, anxiety and stress.

Gamma-aminobutyric acid is thought to have a natural calming effect and is believed to reduce feelings of of anxiety and fear by decreasing neuronal excitability.

It is often used as a natural supplement to promote sleep, improve mood and ease premenstrual symptoms.